Search on: PROTEIN TYROSINE PHOSPHATASES 
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Descriptor English:   Protein Tyrosine Phosphatases 
Descriptor Spanish:   Proteínas Tirosina Fosfatasas 
Descriptor Portuguese:   Proteínas Tirosina Fosfatases 
Synonyms English:   PTPase
Phosphotyrosyl Protein Phosphatase
Protein-Tyrosine Phosphatase
Phosphatase, Phosphotyrosine
Phosphatase, Phosphotyrosyl Protein
Phosphatase, Protein-Tyrosine
Phosphatase, Tyrosyl Phosphoprotein
Phosphatases, Protein Tyrosine
Phosphoprotein Phosphatase, Tyrosyl
Protein Phosphatase, Phosphotyrosyl
Protein Tyrosine Phosphatase
Tyrosine Phosphatases, Protein
Phosphotyrosine Phosphatase
Protein-Tyrosine-Phosphatase
Tyrosyl Phosphoprotein Phosphatase  
Tree Number:   D08.811.277.352.650.775
Definition English:   An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2008(1985) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   29866 
Unique Identifier:   D017027 

Occurrence in VHL:
 

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